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Elie Nader obtained a PhD in Physiology in 2019 (Lyon). After two years as temporary lecturer, he was recruited in 2021 as a senior lecturer in Exercise Physiology in the Vascular Biology and Red Blood Cell Team (University Claude Bernard Lyon 1).
He mainly works on the mechanisms of erythrocyte senescence and their consequences on vascular function. His research activities are focused on pathological context, particularly on red blood cell disorders (Sickle Cell Disease, Hereditary Spherocytosis), but also on the effects of acute and chronic altitude exposure. He also investigates the effects of acute and chronic exercise in endurance athletes and in patients with hematological disorders.
Nationally, he is collaborating with academic (HP2 Laboratory on Grenoble, UMR_S1134 in Pointe à Pitre, Biological Station of Roscoff, European Laboratory of Performance Health and Altitude in Perpignan) and medical (Departments of internal medicine, vascular medecine and exercise medicine in the Hospices Civils of Lyon, Hematological and Oncology pediatric Institute of Lyon, Pointe à Pitre Hospital) institutes. He has also international collaborations with the University of Colorado Anschutz Medical Campus (United-States) and with the German Sport University of Cologne (Germany). He is working with industrial partners including Erytech Pharma (France) and Hartis Pharma (Switzerland).
In September 2021, he had published 21 papers in international journals and had
participated as a speaker in 12 conferences and congresses in France and abroad.
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Elie Nader (elie.nader @ free.fr)
Nationality: French
Institution:
Université Claude Bernard (Lyon 1)
Team: [VBRBC]
Position:
Teacher-researcher
Publications
 
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1. Oxidative stress and altered nitric oxide bioavailability exacerbate red blood cell senescence in sickle cell anemia patients, hence promoting the release of red blood cell microparticles that alter macrovascular function.
2. Plasmapheresis can be an efficient therapeutic tool to treat sickle cell anemia patients suffering from multiple organ failure. This therapeutic efficiency could be attributed to the removal of plasma pro-inflammatory molecules that can affect red blood cell deformability and aggregation properties.
3. Six weeks of adapted training in children with cell anemia is safe and improves breathing efficiency and reduces hemolysis and nitrosative stress.
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