Physical Ability and Fatigue in Health and Disease
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Research areas: Neuromuscular Function, Metabolism, Muscular & Integrative Physiology, Fatigue, Innovative Methods, Models, Various Populations.
The scientific work carried out by the team aims to study and understand, using neuromuscular, modeled approaches, integrative physiology and muscle biology, the determinants of physical fitness and acute or chronic fatigue, in healthy subjects (trained or not, subjected to extreme conditions or particular constraints, ...), the elderly, patients (of multisystemic, neurological, neuromuscular and hematological diseases), subjects with motor disabilities, or temporarily disabled/limited in their daily life (after surgery, ICU stay, etc.). In this context, innovative methods of therapy or intervention using physical activity, localized vibration, neuromuscular stimulation and/or intermittent hypoxia will be implemented.
The etiology of acute fatigue will be at the heart of the scientific interests of the PAF team. We aim to better understand the links between neuromuscular fatigue on the one hand, and sex, hypoxemia, lactate metabolism, pH regulation, muscle performance, strength/speed/power/endurance profiles (collaboration with SPIP team) on the other hand. The study of acute fatigue will also allow the development of innovative investigation methodologies potentially transferable to pathological situations.
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Team Leader Members |
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